Ubushakashatsi bushya bwiswe “Gukoresha Pix-2-Pix GAN mu Kwiga Byimbitse-Bishingiye ku mubiri wose PSMA PET / CT Attenuation Ikosora” iherutse gusohoka mu gitabo cya 15 cya Oncotarget ku ya 7 Gicurasi 2024.
Imirasire ituruka kubushakashatsi bukurikiranye bwa PET / CT mubushakashatsi bwa oncology abarwayi ni impungenge. Muri iri perereza riherutse, itsinda ry’abashakashatsi barimo Kevin C. Ma, Esther Mena, Liza Lindenberg, Nathan S. Lay, Phillip Eclarinal, Deborah E. Citrin, Peter A. Pinto, Bradford J. Wood, William L. Dahut, James L. Gulley, Ravi A. Madan, Peter L. Choyke, Ismail Baris Turkbey, na Stephanie A. Harmon bo mu kigo cy’igihugu gishinzwe kanseri mu kigo cy’ubuzima cy’igihugu berekanye igikoresho cy’ubwenge (AI). Iki gikoresho kigamije kubyara attenuation-yakosowe PET (AC-PET) amashusho avuye kumashusho ya PET (NAC-PET) adakwiye gukosorwa, birashobora kugabanya ibikenewe kuri scan ya CT nkeya.
“Amashusho yakozwe na Ai yakozwe na PET afite ubushobozi bwo kuvura kugira ngo hagabanuke gukosorwa kwa CT scan mu gihe hagumijwe kubika ibimenyetso byerekana ubwiza bw'ishusho ku barwayi ba kanseri ya prostate.”
Uburyo: Kwiga byimbitse algorithm ishingiye kuri 2D Pix-2-Pix itanga imiyoboro ya adversarial net (GAN) yubatswe yakozwe ishingiye kumashusho AC-PET hamwe na NAC-PET. 18F-DCFPyL PSMA (Prostate yihariye membrane antigen) PET-CT ubushakashatsi bwakozwe ku barwayi 302 barwaye kanseri ya prostate yagabanijwemo amahugurwa, kwemeza, no gupima amatsinda (n 183, 60, na 59). Icyitegererezo cyatojwe hakoreshejwe ingamba ebyiri zisanzwe: Standard Uptake Agaciro (SUV) ishingiye na SUV-NYUL ishingiye. Gusikana imikorere itambitse yasuzumwe hifashishijwe ikosa risanzwe risobanura ikosa (NMSE), risobanura ikosa ryuzuye (MAE), icyerekezo gisa n’imiterere (SSIM) hamwe n’ikigereranyo cyerekana urusaku (PSNR). Umuganga wubuvuzi bwa kirimbuzi birashoboka ko yakoze isesengura ryurwego rwinyungu. Ibipimo bya SUV byasuzumwe hifashishijwe ihuriro hagati yitsinda rifitanye isano (ICC), coeffisente isubirwamo (RC), hamwe ningero zivanze kumurongo.
Ibisubizo：Mu itsinda ryigenga ryigenga, hagati ya NMSE, MAE, SSIM, na PSNR bari 13.26%, 3.59%, 0.891, na 26.82. ICC ya SUVmax na SUVmean yari 0.88 na 0.89, byerekana isano ikomeye hagati yumwimerere na AI yakozwe na mashusho yerekana amashusho. Ibintu nkibibanza byangiritse, ubucucike (ibice bya Hounsfield), hamwe no gufata ibisebe byagaragaye ko bigira ingaruka kumakosa ugereranije mubipimo byakozwe na SUV (byose p <0.05).
"AC-PET yakozwe na moderi ya Pix-2-Pix GAN yerekana ibipimo bya SUV bihuza neza n'amashusho y'umwimerere. Amashusho yakozwe na AI yerekana amashusho yerekana ubushobozi bw’ubuvuzi bwo kugabanya ibikenerwa bya CT kugira ngo bikosorwe mu gihe hagumijwe ibimenyetso byerekana ubwiza n’ishusho. ”
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Nkuko twese tubizi, iterambere ryinganda zerekana amashusho yubuvuzi ntaho ritandukaniye niterambere ryibikoresho byubuvuzi - inshinge zitandukanya imiti n’ibikoresho bifasha - bikoreshwa cyane muri uru rwego. Mu Bushinwa, hazwi cyane mu nganda zikora inganda, hari inganda nyinshi zizwi mu gihugu ndetse no mu mahanga kubera gukora ibikoresho byerekana amashusho y’ubuvuzi, harimoLnkMed. Kuva yashingwa, LnkMed yibanze cyane murwego rwo gutera inshinge nyinshi. Itsinda ryubwubatsi bwa LnkMed riyobowe na Ph.D. afite uburambe bwimyaka irenga icumi kandi akora cyane mubushakashatsi niterambere. Ku buyobozi bwe ,.CT inshinge imwe,CT inshinge ebyiri,MRI itandukanya inshinge, naAngiografiya yumuvuduko mwinshi utandukanya inshingeByashizweho hamwe nibi bintu: umubiri ukomeye kandi wuzuye, interineti ikora neza kandi yubwenge, imikorere yuzuye, umutekano muremure, hamwe nigishushanyo kirambye. Turashobora kandi gutanga syringes na tube sthat bihujwe nibirango bizwi bya injeneri za CT, MRI, DSA Hamwe n'imyitwarire yabo itaryarya n'imbaraga zumwuga, abakozi bose ba LnkMed baragutumiye byimazeyo kuza gusura amasoko menshi hamwe.
Igihe cyo kohereza: Gicurasi-14-2024
