Ni iyihe shusho ikora neza mu gupima igaruka rya kanseri ya prostate muri biochemical: PET / CT cyangwa mpMRI?

Dukurikije isesengura riherutse gukorwa, positron emission tomography/computed tomography (PET/CT) na multi-parameter magnetic resonance imaging (mpMRI) bitanga igipimo kimwe cyo kumenya kanseri ya prostate (PCa) ishobora kongera kugaragara.

Abashakashatsi basanze PET/CT ya prostate specific membrane antigen (PSMA) yari ifite igipimo rusange cya 69% cyo kugaragara kwa kanseri ya prostate, ugereranyije na 70% kuri mpMRI.

“Ku bijyanye no gusubira inyuma kw’indwara mu buryo bwa biochemical, uburyo bwombi burakora. Ibisubizo byacu bigaragaza ko nta tandukaniro rigaragara mu mikorere ya DR (igipimo cyo kubona) hagati y’uburyo bubiri bwo gufata amashusho, kandi mpMRI ihendutse cyane mu gihe igumana DR imwe,” nk’uko byanditswe n’umwanditsi wungirije w’ubushakashatsi L. Xu, ukorana n’Ishuri ry’Ubuvuzi, Kaminuza ya Hunan y’Ubuvuzi gakondo bw’Abashinwa, Hunan, Ubushinwa n’abo bakorana.

Ku bijyanye no kongera kwandura kwa PCa mu gace runaka, abanditsi b’ubushakashatsi bavuze ko DR On mpMRI yari hejuru ya 10% (62% ugereranyije na 52%). Abashakashatsi banasanze PSMA PET / CT yagaragaje iterambere rya 18% mu gusuzuma DR Igihe isuzuma lymph node metastasis (50% na 32%, uko bikurikirana). Icyakora, nta na kimwe mu byavumbuwe cyari gifite agaciro mu mibare, nk’uko abanditsi b’ubushakashatsi babivuze.

Abashakashatsi bemeza ko kuba PSMA PET/CT ifite ubushobozi bwo gupima no kumenya ibisebe bito bishobora guha PSMA PET/CT amahirwe mu gupima no kumenya ibisebe bito, ariko kandi bemeza ko kuba ubu buryo buboneka ari ikibazo. MRI ifite ibipimo byinshi ishobora gufasha mu gusuzuma ko PCa ishobora kugaruka mu gace runaka ndetse n'uko igaragara mu buvuzi, ariko abanditsi b'ubushakashatsi bemeza ko itandukaniro ry'abareba kure rishobora kuba ikibazo kuri mpMRI.

Ariko, ibyavuye mu isesengura rusange ry’ibizamini bigaragaza ko uburyo bwombi bufite uruhare mu gusuzuma PCa BCR, kandi byerekeza ku bushakashatsi bw’ejo hazaza bushobora gutanga ibisobanuro birambuye kuri uru rwego.

Xu na bagenzi be bashimangiye ingaruka zikomeye z'ibyavuye mu bushakashatsi ku buvuzi. Bagaragaje ko ubushobozi bwo gusuzuma PSMA PET/CT na mpMRI bungana bugaragaza akamaro k'uburyo bwombi mu gupima BCR ku barwayi ba PCa. Ariko, bashimangiye ko hakenewe ubushakashatsi bwimbitse kugira ngo hasuzumwe uburyo buhendutse, bworoshye gukoreshwa, n'uburyo buhendutse bwo gukoresha ubu buryo bwo gufotora.

Ubwo baganiraga ku mbogamizi z’ubushakashatsi, abanditsi bemeye ko umubare muto w’abarwayi 290 ari wo waturutse ku gusesengura ubushakashatsi bugereranya BCR mu matsinda y’abarwayi amwe. Banavuze ko hashobora kubaho kubogama mu bisubizo bitewe n’uburyo butandukanye bwo gufata amashusho n’imiterere y’abarwayi mu bushakashatsi butandatu basuzumye.

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Bitewe n'iterambere ry'ikoranabuhanga ryo gufata amashusho mu buvuzi, hasohotse amasosiyete menshi ashobora gutanga ibikoresho byo gufata amashusho, nk'inshinge n'inshinge.LnkMedIkoranabuhanga mu by'ubuvuzi ni rimwe muri yo. Dutanga urutonde rwuzuye rw'ibikoresho by'inyongera byo gusuzuma indwara:Inshinge imwe ya CT，Inshinge ya CT ifite imitwe ibiri,Inshinge za MRInaInshinge ziterwa n'umuvuduko mwinshi wa DSAZikorana neza n'ibirango bitandukanye bya scanner bya CT/MRI nka GE, Philips, Siemens. Uretse injector, tunatanga seringe na tube bishobora gukoreshwa ku bicuruzwa bitandukanye bya injector birimo Medrad/Bayer, Mallinckrodt/Guerbet, Nemoto, Medtron, Ulrich.
Ibi bikurikira ni byo dushoboye cyane: igihe cyo gutanga ibicuruzwa byihuse; Impamyabushobozi zuzuye zo kwemeza ibicuruzwa, uburambe bw'imyaka myinshi mu kohereza ibicuruzwa mu mahanga, inzira nziza yo kugenzura ibicuruzwa, ibicuruzwa bikora neza, twishimiye cyane ikibazo cyawe.